Cyclic Olefin Polymer (COC) - New high-barrier blister composite packaging material

China Packaging Network compile: With the rapid development of the packaging industry, pharmaceutical blister packaging has become one of the mainstream, but the plastic film for pharmaceutical blister packaging requirements are very strict: to be both thin and has sufficient barrier properties, but also easy to tear It is not easy to crack and show high transparency, so that medicines can be seen at a glance. Therefore, pharmaceutical companies are very careful to choose blister packaging materials.

Internationally, a material called COC is being tested. It is a kind of material. The biggest difference from common plastic materials is that the chemical chain of COC material is circular, while the chemical chain of ordinary PP or PE is linear. Due to its special structure, it has determined that the material has special properties that are different from general plastics, and it has the characteristics of transparency, heat resistance, acid and alkali resistance, and strength. It is a kind of material with high moisture resistance and good thermoforming performance. It can be shaped like a PVC hard sheet and has good dimensional stability. It is a crystal-like transparent material, and its transparency is still high after being dyed as a blister pack.

However, although it has good thermoforming properties, it is inherently fragile, so it is often compounded with polypropylene (PP) to maintain its shape, and can also be compounded with chlorotrifluoroethylene homopolymers. COC can be molded on most high-performance thermoforming equipment. Because of its easy moldability, COC can be an ideal alternative to heat-sealed blister packaging and cold-formed aluminum-plastic composite packaging.

According to reports, Tekni-Plex, a US-based plastic film company, has used COC (provided by Ticona, Germany) and chlorotrifluoroethylene in the production of high-barrier blister-type composite packaging films, making the water vapor transmission rate of blister packs significantly greater. reduce. The application of this new type of blister packaging film is pharmaceutical packaging. Compared with the general PVC and PVDC (polyvinylidene chloride) blocked blister packaging, the COC is successfully developed in the blister packaging, not only the water vapor transmission rate of the material is very low, but also the thickness can be reduced. increase. Among them, Tekni's products, COC thickness range of 200,250,300,350μm, PCTFE thickness of 10-100μm. When the COC thickness was 300 μm and the PCTFE thickness was 23 μm, the water vapor transmission rate was 0.098 mg/cavity/day. As a control, the water vapor transmission rate of the 250 μm PVC/23 μm PCTFE film was 0.200 mg/cavity/day.

Source of information: pack.cn