The national "Protein Research" major scientific research project-"Protein High Resolution Structure Determination and Efficient Preparation Technology" project was officially launched in Han.
The project was led by the Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences, and jointly undertaken by the Institute of High Energy Physics, Chinese Academy of Sciences, Shanghai Institute of Organic Chemistry, and Fudan University. The chief scientist of the project is Liu Maili, a researcher of Wuhan Institute of Mathematics. The research team has gathered a group of young and middle-aged academic backbones in related fields, including 2 outstanding youth fund winners, 3 Chinese Academy of Sciences "hundred people plan" candidates, main backbone members The average age is 36 years old. The panelists (8) included 2 academicians Wang Dacheng and Zhao Guoping. In the next five years, the project team will focus on researching new technologies and methods for protein three-dimensional structure determination, as well as matching protein efficient preparation technology.
The study of protein structure is one of the most demonstrable fields in life science research in China. In 1974, Chinese scientists successfully determined the three-dimensional crystal structure of porcine insulin and achieved artificial synthesis; in recent years, a series of internationally influential results have been achieved, especially the systematic study of SARS-related protein structures, showing that we are facing public surprises. Research strength at the time of the incident. At the same time, China also has great development in the construction of basic platforms, and has an innovative research team that combines old, Chinese and young people. Nevertheless, we still have a large gap in terms of scale and investment compared with developed countries.
Although the international protein structure analysis has developed rapidly, it is still not as fast as the development of genome research, and it is difficult to meet various needs in related fields. The lack of protein measurement capabilities has severely restricted the development of protein science in a certain sense. As of June 2008, the number of proteins whose structure has been resolved accounted for only 0.75% of the sequences found, compared with 1.5% three years ago. The lack of ability to determine protein structure has severely restricted the development of protein science in a sense.
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